The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation

Mammalian DNMT1 is mainly responsible for maintenance DNA methylation that is critical in maintaining stem cell pluripotency and controlling lineage specification during early embryonic development. A number of studies have demonstrated that DNMT1 is an auto-inhibited enzyme and its enzymatic activi...

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Detalles Bibliográficos
Autores principales: Xie, Si, Qian, Chengmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316679/
https://www.ncbi.nlm.nih.gov/pubmed/30513966
http://dx.doi.org/10.3390/genes9120600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316679/
https://www.ncbi.nlm.nih.gov/pubmed/30513966
http://dx.doi.org/10.3390/genes9120600

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