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Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative

Pulmonary arterial hypertension (PAH) is a chronic cardiovascular disease that displays inflammatory components, which contributes to the difficulty of adequate treatment with the available therapeutic arsenal. In this context, the N-acylhydrazone derivative LASSBio-1359 was previously described as...

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Detalles Bibliográficos
Autores principales: Bastos, Isadora T. S., Pinheiro, Pedro de Sena M., Costa, Fanny N., Rocha, Miguel D., Sant’Anna, Carlos Mauricio R., Braz, Delson, Souza, Everton T., Martins, Marco A., Barreiro, Eliezer J., Ferreira, Fabio F., Barroso, Regina C., Fraga, Carlos A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316713/
https://www.ncbi.nlm.nih.gov/pubmed/30388818
http://dx.doi.org/10.3390/ph11040119