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Pretargeted Imaging with Gallium-68—Improving the Binding Capability by Increasing the Number of Tetrazine Motifs

The inverse electron-demand Diels-Alder reaction between 1,2,4,5-tetrazine (Tz) and trans-cyclooct-2-ene (TCO) has gained increasing attraction among extensive studies on click chemistry due to its exceptionally fast reaction kinetics and high selectivity for in vivo pretargeting applications includ...

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Detalles Bibliográficos
Autores principales: Summer, Dominik, Mayr, Sonja, Petrik, Milos, Rangger, Christine, Schoeler, Katia, Vieider, Lisa, Matuszczak, Barbara, Decristoforo, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316846/
https://www.ncbi.nlm.nih.gov/pubmed/30314332
http://dx.doi.org/10.3390/ph11040102