Ponatinib Inhibits Multiple Signaling Pathways Involved in STAT3 Signaling and Attenuates Colorectal Tumor Growth

Signal transducer and activator of transcription 3 (STAT3) signaling is a major driver of colorectal cancer (CRC) growth, however therapeutics, which can effectively target this pathway, have so far remained elusive. Here, we performed an extensive screen for STAT3 inhibitors among a library of 1167...

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Detalles Bibliográficos
Autores principales: Tan, Fiona H., Putoczki, Tracy L., Lou, Jieqiong, Hinde, Elizabeth, Hollande, Frédéric, Giraud, Julie, Stylli, Stanley S., Paradiso, Lucia, Zhu, Hong-Jian, Sieber, Oliver M., Luwor, Rodney B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316865/
https://www.ncbi.nlm.nih.gov/pubmed/30572654
http://dx.doi.org/10.3390/cancers10120526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316865/
https://www.ncbi.nlm.nih.gov/pubmed/30572654
http://dx.doi.org/10.3390/cancers10120526

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