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Heparanase: A Multitasking Protein Involved in Extracellular Matrix (ECM) Remodeling and Intracellular Events

Heparanase (HPSE) has been defined as a multitasking protein that exhibits a peculiar enzymatic activity towards HS chains but which simultaneously performs other non-enzymatic functions. Through its enzymatic activity, HPSE catalyzes the cutting of the side chains of heparan sulfate (HS) proteoglyc...

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Detalles Bibliográficos
Autores principales: Masola, Valentina, Bellin, Gloria, Gambaro, Giovanni, Onisto, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316874/
https://www.ncbi.nlm.nih.gov/pubmed/30487472
http://dx.doi.org/10.3390/cells7120236