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Complement factors C3a and C5a mimick a proinflammatory microenvironment and increase HBV IGRA sensitivity

BACKGROUND: Hepatitis B virus (HBV) infections represent a global health problem and chronic hepatitis B (CHB) leads to liver cirrhosis and hepatocellular carcinoma. Thus, timely diagnosis of hepatitis B is crucial to ensure adequate treatment. We developed a powerful and rapid whole blood-based cyt...

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Detalles Bibliográficos
Autores principales: Bröker, Katharina, Terzenbach, Robin, Bentzien, Frank, Lüth, Stefan, Dammermann, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317231/
https://www.ncbi.nlm.nih.gov/pubmed/30602374
http://dx.doi.org/10.1186/s12967-018-1752-8