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The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans

Piwi-interacting RNAs (piRNAs) engage Piwi proteins to suppress transposons and nonself nucleic acids and maintain genome integrity and are essential for fertility in a variety of organisms. In Caenorhabditis elegans, most piRNA precursors are transcribed from two genomic clusters that contain thous...

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Detalles Bibliográficos
Autores principales: Weng, Chenchun, Kosalka, Joanna, Berkyurek, Ahmet C., Stempor, Przemyslaw, Feng, Xuezhu, Mao, Hui, Zeng, Chenming, Li, Wen-Jun, Yan, Yong-Hong, Dong, Meng-Qiu, Morero, Natalia Rosalía, Zuliani, Cecilia, Barabas, Orsolya, Ahringer, Julie, Guang, Shouhong, Miska, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317315/
https://www.ncbi.nlm.nih.gov/pubmed/30567997
http://dx.doi.org/10.1101/gad.319293.118