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Development and validation of a salivary tau biomarker in Alzheimer's disease

INTRODUCTION: Total tau (t-tau) and phosphorylated tau (p-tau) are abnormally elevated in the brain and cerebrospinal fluid of individuals with Alzheimer's disease (AD). Tau is also present in the salivary gland tissue and saliva, and salivary measures might produce an accurate, accessible, and...

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Detalles Bibliográficos
Autores principales: Pekeles, Heather, Qureshi, Hamid Y., Paudel, Hemant K., Schipper, Hyman M., Gornistky, Mervyn, Chertkow, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317325/
https://www.ncbi.nlm.nih.gov/pubmed/30623019
http://dx.doi.org/10.1016/j.dadm.2018.03.003