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Development and validation of a salivary tau biomarker in Alzheimer's disease
INTRODUCTION: Total tau (t-tau) and phosphorylated tau (p-tau) are abnormally elevated in the brain and cerebrospinal fluid of individuals with Alzheimer's disease (AD). Tau is also present in the salivary gland tissue and saliva, and salivary measures might produce an accurate, accessible, and...
Autores principales: | Pekeles, Heather, Qureshi, Hamid Y., Paudel, Hemant K., Schipper, Hyman M., Gornistky, Mervyn, Chertkow, Howard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317325/ https://www.ncbi.nlm.nih.gov/pubmed/30623019 http://dx.doi.org/10.1016/j.dadm.2018.03.003 |
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