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Single-cell RNA-seq analysis reveals the progression of human osteoarthritis

OBJECTIVES: Understanding the molecular mechanisms underlying human cartilage degeneration and regeneration is helpful for improving therapeutic strategies for treating osteoarthritis (OA). Here, we report the molecular programmes and lineage progression patterns controlling human OA pathogenesis us...

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Detalles Bibliográficos
Autores principales: Ji, Quanbo, Zheng, Yuxuan, Zhang, Guoqiang, Hu, Yuqiong, Fan, Xiaoying, Hou, Yu, Wen, Lu, Li, Li, Xu, Yameng, Wang, Yan, Tang, Fuchou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317448/
https://www.ncbi.nlm.nih.gov/pubmed/30026257
http://dx.doi.org/10.1136/annrheumdis-2017-212863