Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A

N-myristoylation is the covalent addition of a 14-carbon saturated fatty acid (myristate) to the N-terminal glycine of specific protein substrates by N-myristoyltransferase (NMT) and plays an important role in protein regulation by controlling localization, stability, and interactions. We developed...

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Detalles Bibliográficos
Autores principales: Goya Grocin, Andrea, Serwa, Remigiusz A., Morales Sanfrutos, Julia, Ritzefeld, Markus, Tate, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317481/
https://www.ncbi.nlm.nih.gov/pubmed/30341083
http://dx.doi.org/10.1074/mcp.RA118.001043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317481/
https://www.ncbi.nlm.nih.gov/pubmed/30341083
http://dx.doi.org/10.1074/mcp.RA118.001043

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