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Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A
N-myristoylation is the covalent addition of a 14-carbon saturated fatty acid (myristate) to the N-terminal glycine of specific protein substrates by N-myristoyltransferase (NMT) and plays an important role in protein regulation by controlling localization, stability, and interactions. We developed...
Autores principales: | Goya Grocin, Andrea, Serwa, Remigiusz A., Morales Sanfrutos, Julia, Ritzefeld, Markus, Tate, Edward W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317481/ https://www.ncbi.nlm.nih.gov/pubmed/30341083 http://dx.doi.org/10.1074/mcp.RA118.001043 |
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