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Determining the amphipol distribution within membrane-protein fibre samples using small-angle neutron scattering
Detergent micelles can solubilize membrane proteins, but there is always a need for a pool of free detergent at the critical micellar concentration to maintain the micelle–monomer equilibrium. Amphipol polymeric surfactants (APols) have been developed to replace conventional detergents in membrane-p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317593/ https://www.ncbi.nlm.nih.gov/pubmed/30605133 http://dx.doi.org/10.1107/S205979831800476X |