Cargando…

High PLK4 expression promotes tumor progression and induces epithelial-mesenchymal transition by regulating the Wnt/β-catenin signaling pathway in colorectal cancer

Polo-like kinase 4 (PLK4) has been identified as an oncogene, which is overexpressed in various types of human cancer; however, its role in colorectal cancer (CRC) development remains unknown. The present study demonstrated that PLK4 protein expression was upregulated in CRC tissues compared with in...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Zhibin, Zhang, Hongwei, Fan, Pan, Huang, Qibo, Dong, Keshuai, Qi, Yongqiang, Song, Jia, Chen, Lin, Liang, Huifang, Chen, Xiaoping, Zhang, Zhanguo, Zhang, Bixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317648/
https://www.ncbi.nlm.nih.gov/pubmed/30570110
http://dx.doi.org/10.3892/ijo.2018.4659