High PLK4 expression promotes tumor progression and induces epithelial-mesenchymal transition by regulating the Wnt/β-catenin signaling pathway in colorectal cancer

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Polo-like kinase 4 (PLK4) has been identified as an oncogene, which is overexpressed in various types of human cancer; however, its role in colorectal cancer (CRC) development remains unknown. The present study demonstrated that PLK4 protein expression was upregulated in CRC tissues compared with in...

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Detalles Bibliográficos
Autores principales: Liao, Zhibin, Zhang, Hongwei, Fan, Pan, Huang, Qibo, Dong, Keshuai, Qi, Yongqiang, Song, Jia, Chen, Lin, Liang, Huifang, Chen, Xiaoping, Zhang, Zhanguo, Zhang, Bixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317648/
https://www.ncbi.nlm.nih.gov/pubmed/30570110
http://dx.doi.org/10.3892/ijo.2018.4659
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