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Genipin protects against H(2)O(2)-induced oxidative damage in retinal pigment epithelial cells by promoting Nrf2 signaling

Oxidative stress serves a vital function in the pathogenesis of age-related macular degeneration (AMD); genipin (GP) possesses antioxidative properties. The present study aimed to investigate the effects of GP on retinal pigment epithelial (RPE) cells induced by H(2)O(2) and the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Zhao, Hailan, Wang, Ruiqing, Ye, Mingxia, Zhang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317649/
https://www.ncbi.nlm.nih.gov/pubmed/30569096
http://dx.doi.org/10.3892/ijmm.2018.4027