Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and is an antitumor drug that induces apoptosis in tumor cells with minimal or no effects on normal cells. Here, it is demonstrated that 6-shogaol (6-sho), a bioactive component of ginger, exerte...

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Detalles Bibliográficos
Autores principales: Nazim, Uddin MD., Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317668/
https://www.ncbi.nlm.nih.gov/pubmed/30483736
http://dx.doi.org/10.3892/ijmm.2018.3994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317668/
https://www.ncbi.nlm.nih.gov/pubmed/30483736
http://dx.doi.org/10.3892/ijmm.2018.3994

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