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Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and is an antitumor drug that induces apoptosis in tumor cells with minimal or no effects on normal cells. Here, it is demonstrated that 6-shogaol (6-sho), a bioactive component of ginger, exerte...
Autores principales: | Nazim, Uddin MD., Park, Sang-Youel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317668/ https://www.ncbi.nlm.nih.gov/pubmed/30483736 http://dx.doi.org/10.3892/ijmm.2018.3994 |
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