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Physiological function of myocilin and its role in the pathogenesis of glaucoma in the trabecular meshwork (Review)

Myocilin is highly expressed in the trabecular meshwork (TM), which plays an important role in the regulation of intraocular pressure (IOP). Myocilin abnormalities may cause dysfunction of the TM, potentially leading to increased IOP. High IOP is a well-known primary risk factor for glaucoma. Myocil...

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Detalles Bibliográficos
Autores principales: Wang, Hongwei, Li, Mingzhe, Zhang, Zhenzhen, Xue, Haifeng, Chen, Xing, Ji, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317685/
https://www.ncbi.nlm.nih.gov/pubmed/30483726
http://dx.doi.org/10.3892/ijmm.2018.3992