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Melatonin regulation of transcription in the reversal of morphine tolerance: Microarray analysis of differential gene expression
Tolerance and associated hyperalgesia induced by long-term morphine administration substantially restrict the clinical use of morphine in pain treatment. Melatonin, a neurohormone released by the pineal gland, has been demonstrated to attenuate anti-nociceptive morphine tolerance. The present study...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317689/ https://www.ncbi.nlm.nih.gov/pubmed/30569162 http://dx.doi.org/10.3892/ijmm.2018.4030 |