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Melatonin regulation of transcription in the reversal of morphine tolerance: Microarray analysis of differential gene expression

Tolerance and associated hyperalgesia induced by long-term morphine administration substantially restrict the clinical use of morphine in pain treatment. Melatonin, a neurohormone released by the pineal gland, has been demonstrated to attenuate anti-nociceptive morphine tolerance. The present study...

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Detalles Bibliográficos
Autores principales: Cheng, Yu-Che, Tsai, Ru-Yin, Sung, Yen-Tseng, Chen, Ing-Jung, Tu, Tzu-Yi, Mao, Ya-Yuan, Wong, Chih-Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317689/
https://www.ncbi.nlm.nih.gov/pubmed/30569162
http://dx.doi.org/10.3892/ijmm.2018.4030