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Ginsenoside Rg1 protects against H(2)O(2)-induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Oxidative stress and neuroinflammation are important in the pathogenesis of ageing and age-related neurodegenerative diseases, including Alzheimer’s disease. NADPH oxidase 2 (NOX2) is a major source of reactive oxygen species (ROS) in the brain. The nucleotide-binding oligomerisation domain (NOD)-li...

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Detalles Bibliográficos
Autores principales: Xu, Tan-Zhen, Shen, Xiao-Yan, Sun, Ling-Ling, Chen, Ya-Li, Zhang, Bi-Qiong, Huang, Da-Ke, Li, Wei-Zu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317692/
https://www.ncbi.nlm.nih.gov/pubmed/30535505
http://dx.doi.org/10.3892/ijmm.2018.4005