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Targeting retinoblastoma protein phosphorylation in combination with EGFR inhibition in pancreatic cancer cells
Pancreatic ductal adenocarcinoma (PDAC) remains a particularly lethal disease that is resistant to targeted therapies. Tyrosine kinase inhibitors (TKIs), including erlotinib and gefitinib, which block the action of the human epidermal growth factor receptor type 1 receptor, provide small increases i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317693/ https://www.ncbi.nlm.nih.gov/pubmed/30535494 http://dx.doi.org/10.3892/ijo.2018.4658 |