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Targeting retinoblastoma protein phosphorylation in combination with EGFR inhibition in pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) remains a particularly lethal disease that is resistant to targeted therapies. Tyrosine kinase inhibitors (TKIs), including erlotinib and gefitinib, which block the action of the human epidermal growth factor receptor type 1 receptor, provide small increases i...

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Detalles Bibliográficos
Autores principales:	Thomas, Nimmi A., Abraham, Rita G., Dedi, Brixhilda, Krucher, Nancy A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317693/ https://www.ncbi.nlm.nih.gov/pubmed/30535494 http://dx.doi.org/10.3892/ijo.2018.4658

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