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GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing
Mutations in human GRXCR2, which encodes a protein of undetermined function, cause hearing loss by unknown mechanisms. We found that mouse GRXCR2 localizes to the base of the stereocilia, which are actin-based mechanosensing organelles in cochlear hair cells that convert sound-induced vibrations int...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317715/ https://www.ncbi.nlm.nih.gov/pubmed/30380417 http://dx.doi.org/10.1016/j.celrep.2018.09.063 |