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Brief Local Application of Progesterone via a Wearable Bioreactor Induces Long-Term Regenerative Response in Adult Xenopus Hindlimb

The induction of limb repair in adult vertebrates is a pressing, unsolved problem. Here, we characterize the effects of an integrated device that delivers drugs to severed hindlimbs of adult Xenopus laevis, which normally regenerate cartilaginous spikes after amputation. A wearable bioreactor contai...

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Detalles Bibliográficos
Autores principales: Celia, Herrera-Rincon, Golding, Annie S., Moran, Kristine M., Harrison, Christina, Martyniuk, Christopher J., Guay, Justin A., Zaltsman, Julia, Carabello, Hayley, Kaplan, David L., Levin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317729/
https://www.ncbi.nlm.nih.gov/pubmed/30404012
http://dx.doi.org/10.1016/j.celrep.2018.10.010