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Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection

Shigella spp. are pathogenic bacteria that cause bacillary dysentery in humans by invading the colonic and rectal mucosa where they induce dramatic inflammation. Here, we have analyzed the role of the soluble PRR Pentraxin 3 (PTX3), a key component of the humoral arm of innate immunity. Mice that ha...

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Detalles Bibliográficos
Autores principales: Ciancarella, Valeria, Lembo-Fazio, Luigi, Paciello, Ida, Bruno, Anna-Karin, Jaillon, Sébastien, Berardi, Sara, Barbagallo, Marialuisa, Meron-Sudai, Shiri, Cohen, Dani, Molinaro, Antonio, Rossi, Giacomo, Garlanda, Cecilia, Bernardini, Maria Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317801/
https://www.ncbi.nlm.nih.gov/pubmed/30532257
http://dx.doi.org/10.1371/journal.ppat.1007469