Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis

Nonalcoholic fatty liver disease (NAFLD) is characterized by abnormal accumulation of triglycerides (TG) in the liver and other metabolic syndrome symptoms, but its molecular genetic causes are not completely understood. Here, we show that mice deficient for ubiquitin ligase (E3) Smad ubiquitin regu...

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Detalles Bibliográficos
Autores principales: Zhu, Kun, Tang, Yi, Xu, Xuan, Dang, Hien, Tang, Liu-Ya, Wang, Xiang, Wang, Xin Wei, Zhang, Ying E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317813/
https://www.ncbi.nlm.nih.gov/pubmed/30566427
http://dx.doi.org/10.1371/journal.pbio.3000091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317813/
https://www.ncbi.nlm.nih.gov/pubmed/30566427
http://dx.doi.org/10.1371/journal.pbio.3000091

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