Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability

The yeast Mre11-Rad50-Xrs2 (MRX) complex has structural, signaling, and catalytic functions in the response to DNA damage. Xrs2, the eukaryotic-specific component of the complex, is required for nuclear import of Mre11 and Rad50 and to recruit the Tel1 kinase to damage sites. We show that nuclear-lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Julyun, Lee, So Jung, Rothstein, Rodney, Symington, Lorraine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317890/
https://www.ncbi.nlm.nih.gov/pubmed/30428339
http://dx.doi.org/10.1016/j.celrep.2018.10.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317890/
https://www.ncbi.nlm.nih.gov/pubmed/30428339
http://dx.doi.org/10.1016/j.celrep.2018.10.030

Ejemplares similares