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Alternative RNA splicing of the GIT1 gene is associated with neuroendocrine prostate cancer

Potent androgen receptor pathway inhibition (ARPI) therapies have given rise to a lethal, aggressive subtype of castration‐resistant prostate cancer (CRPC) called treatment‐induced neuroendocrine prostate cancer (t‐NEPC). Now, t‐NEPC poses a major clinical problem as approximately 20% of CRPC cases...

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Detalles Bibliográficos
Autores principales: Lee, Ahn R., Gan, Yu, Xie, Ning, Ramnarine, Varune R., Lovnicki, Jessica M., Dong, Xuesen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317919/
https://www.ncbi.nlm.nih.gov/pubmed/30417466
http://dx.doi.org/10.1111/cas.13869