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Development of a T‐cell receptor multimer with high avidity for detecting a naturally presented tumor‐associated antigen on osteosarcoma cells

For efficacy of peptide vaccination immunotherapy for patients with cancer, endogenous expression of the target peptide/human leukocyte antigen (HLA) on cancer cells is required. However, it is difficult to evaluate the expression status of a peptide/HLA complex because of the lack of a soluble T‐ce...

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Detalles Bibliográficos
Autores principales: Watanabe, Kazue, Tsukahara, Tomohide, Toji, Shingo, Saitoh, Shogo, Hirohashi, Yoshihiko, Nakatsugawa, Munehide, Kubo, Terufumi, Kanaseki, Takayuki, Kameshima, Hidekazu, Terui, Takeshi, Sato, Noriyuki, Torigoe, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317924/
https://www.ncbi.nlm.nih.gov/pubmed/30375705
http://dx.doi.org/10.1111/cas.13854