Cargando…

Palbociclib enhances activin‐SMAD‐induced cytostasis in estrogen receptor‐positive breast cancer

Cyclin‐dependent kinase (CDK) 4 and CDK6 inhibitors are effective therapeutic options for hormone receptor (HR)‐positive, human epidermal growth factor receptor 2 (HER2)‐negative advanced breast cancer. Although CDK4/6 inhibitors mainly target the cyclin D‐CDK4/6‐retinoblastoma tumor suppressor prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Harada, Mayumi, Morikawa, Masato, Ozawa, Takayuki, Kobayashi, Mai, Tamura, Yusuke, Takahashi, Kei, Tanabe, Masahiko, Tada, Keiichiro, Seto, Yasuyuki, Miyazono, Kohei, Koinuma, Daizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317929/
https://www.ncbi.nlm.nih.gov/pubmed/30343527
http://dx.doi.org/10.1111/cas.13841