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Immunoregulatory Protein B7-H3 Regulates Cancer Stem Cell Enrichment and Drug Resistance through MVP-mediated MEK Activation

B7-H3 is a tumor promoting glycoprotein that is expressed at low levels in most normal tissues but is overexpressed in various human cancers which is associated with disease progression and poor patient outcome. Although numerous publications have reported the correlation between B7-H3 and cancer pr...

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Detalles Bibliográficos
Autores principales: Liu, Zixing, Zhang, Wenling, Phillips, Joshua B., Arora, Ritu, McClellan, Steven, Li, Jiangfeng, Kim, Jin-Hwan, Sobol, Robert W., Tan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318029/
https://www.ncbi.nlm.nih.gov/pubmed/30082909
http://dx.doi.org/10.1038/s41388-018-0407-9