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Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells

Mitochondrial damage is caused by changes in the micro-environmental conditions during tumor progression. Cancer cells require mechanisms for mitochondrial quality control during this process; however, how mitochondrial integrity is maintained is unclear. Here we show that E2F3d, a previously uniden...

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Detalles Bibliográficos
Autores principales: Araki, Keigo, Kawauchi, Keiko, Sugimoto, Wataru, Tsuda, Daisuke, Oda, Hiroya, Yoshida, Ryosuke, Ohtani, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318215/
https://www.ncbi.nlm.nih.gov/pubmed/30740539
http://dx.doi.org/10.1038/s42003-018-0246-9