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DNA Binding and Phosphorylation Regulate the Core Structure of the NF-κB p50 Transcription Factor
The NF-κB transcription factors are known to be extensively phosphorylated, with dynamic site-specific modification regulating their ability to dimerize and interact with DNA. p50, the proteolytic product of p105 (NF-κB1), forms homodimers that bind DNA but lack intrinsic transactivation function, f...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318249/ https://www.ncbi.nlm.nih.gov/pubmed/29873020 http://dx.doi.org/10.1007/s13361-018-1984-0 |