Cargando…

Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles

The desymmetrization of meso-compounds is a useful synthetic method, as illustrated by numerous applications of this strategy in natural product synthesis. Cu-catalyzed allylic desymmetrizations enable the enantioselective formation of carbon-carbon bonds, but these transformations are limited in su...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacques, Reece, Pullin, Robert D. C., Fletcher, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318275/
https://www.ncbi.nlm.nih.gov/pubmed/30604753
http://dx.doi.org/10.1038/s41467-018-07871-x