Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity

The presence of aberrant number of centrioles is a recognized cause of aneuploidy and hallmark of cancer. Hence, centriole duplication needs to be tightly regulated. It has been proposed that centriole separation limits centrosome duplication. The mechanism driving centriole separation is poorly und...

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Detalles Bibliográficos
Autores principales: Vitiello, Elisa, Moreau, Philippe, Nunes, Vanessa, Mettouchi, Amel, Maiato, Helder, Ferreira, Jorge G., Wang, Irène, Balland, Martial
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318293/
https://www.ncbi.nlm.nih.gov/pubmed/30604763
http://dx.doi.org/10.1038/s41467-018-07965-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318293/
https://www.ncbi.nlm.nih.gov/pubmed/30604763
http://dx.doi.org/10.1038/s41467-018-07965-6

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