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Beta-Hydroxybutyrate Promotes Proliferation, Migration and Stemness in a Subpopulation of 5FU Treated SW480 Cells: Evidence for Metabolic Plasticity in Colon Cancer

BACKGROUND: Beta-hydroxybutyrate (BHB) as a ketone body is the metabolic fuel in oxidative phosphorylation pathway. So far the effects of BHB on the biology of tumor cells is contradictory. Therefore, we investigated the effect of BHB on viability, metabolism, proliferation and migration of 5FU trea...

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Detalles Bibliográficos
Autores principales: Shakery, Azam, Pourvali, Katayoun, Ghorbani, Arman, Fereidani, Samira Sadat, Zand, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318419/
https://www.ncbi.nlm.nih.gov/pubmed/30486639
http://dx.doi.org/10.31557/APJCP.2018.19.11.3287