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High Oct4 expression: implications in the pathogenesis of neuroblastic tumours

BACKGROUND: Neuroblastic tumours (NBTs) are paediatric solid tumours derived from embryonic neural crest cells which harbour their own cancer stem cells (CSC). There is evidence indicating that CSC may be responsible for tumour progression, chemotherapy resistance and recurrence in NBTs. Oct4 is a t...

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Detalles Bibliográficos
Autores principales: Monferrer, Ezequiel, Burgos-Panadero, Rebeca, Blanquer-Maceiras, Maite, Cañete, Adela, Navarro, Samuel, Noguera, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318846/
https://www.ncbi.nlm.nih.gov/pubmed/30606139
http://dx.doi.org/10.1186/s12885-018-5219-3