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Replication stress-induced Exo1 phosphorylation is mediated by Rad53/Pph3 and Exo1 nuclear localization is controlled by 14-3-3 proteins

BACKGROUND: Mechanisms controlling DNA resection at sites of damage and affecting genome stability have been the subject of deep investigation, though their complexity is not yet fully understood. Specifically, the regulatory role of post-translational modifications in the localization, stability an...

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Detalles Bibliográficos
Autores principales: Chappidi, Nagaraja, De Gregorio, Giuseppe, Ferrari, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318887/
https://www.ncbi.nlm.nih.gov/pubmed/30622624
http://dx.doi.org/10.1186/s13008-018-0044-2