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DBS: a fast and informative segmentation algorithm for DNA copy number analysis

BACKGROUND: Genome-wide DNA copy number changes are the hallmark events in the initiation and progression of cancers. Quantitative analysis of somatic copy number alterations (CNAs) has broad applications in cancer research. With the increasing capacity of high-throughput sequencing technologies, fa...

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Detalles Bibliográficos
Autores principales: Ruan, Jun, Liu, Zhen, Sun, Ming, Wang, Yue, Yue, Junqiu, Yu, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318921/
https://www.ncbi.nlm.nih.gov/pubmed/30606105
http://dx.doi.org/10.1186/s12859-018-2565-8