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DBS: a fast and informative segmentation algorithm for DNA copy number analysis
BACKGROUND: Genome-wide DNA copy number changes are the hallmark events in the initiation and progression of cancers. Quantitative analysis of somatic copy number alterations (CNAs) has broad applications in cancer research. With the increasing capacity of high-throughput sequencing technologies, fa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318921/ https://www.ncbi.nlm.nih.gov/pubmed/30606105 http://dx.doi.org/10.1186/s12859-018-2565-8 |