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PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells

BACKGROUND: Tendon stem/progenitor cells (TSPC) exhibit a low proliferative response to heal tendon injury, leading to limited regeneration outcomes. Exogenous growth factors that activate TSPC proliferation have emerged as a promising approach for treatment. Here, we evaluated the pigment epithelia...

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Detalles Bibliográficos
Autores principales: Ho, Tsung-Chuan, Tsai, Shawn H., Yeh, Shu-I, Chen, Show-Li, Tung, Kwang-Yi, Chien, Hsin-Yu, Lu, Yung-Chang, Huang, Chang-Hung, Tsao, Yeou-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318926/
https://www.ncbi.nlm.nih.gov/pubmed/30606221
http://dx.doi.org/10.1186/s13287-018-1110-z