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Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosis

BACKGROUND: Accurate drug susceptibility testing (DST) of Mycobacterium tuberculosis in clinical specimens and culture isolates to first-line drugs is crucial for diagnosis and management of multidrug-resistant tuberculosis (MDR-TB). Resistance of M. tuberculosis to rifampicin is mainly due to mutat...

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Detalles Bibliográficos
Autores principales: Al-Mutairi, Noura M., Ahmad, Suhail, Mokaddas, Eiman, Eldeen, Hanaa S., Joseph, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318973/
https://www.ncbi.nlm.nih.gov/pubmed/30606116
http://dx.doi.org/10.1186/s12879-018-3638-z