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Methylation of p16 (ink4a) promoter is independent of human papillomavirus DNA physical state: a comparison between cervical pre-neoplastic and neoplastic samples
BACKGROUND Epigenetic modifications in host cells, like p16 (ink4a) methylation, have been considered as putative complementary mechanisms for cancer development. Because only a small proportion of infected women develop cervical cancer, other factors might be involved in carcinogenesis, either inde...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319029/ https://www.ncbi.nlm.nih.gov/pubmed/30569945 http://dx.doi.org/10.1590/0074-02760180456 |