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Methylation of p16 (ink4a) promoter is independent of human papillomavirus DNA physical state: a comparison between cervical pre-neoplastic and neoplastic samples

BACKGROUND Epigenetic modifications in host cells, like p16 (ink4a) methylation, have been considered as putative complementary mechanisms for cancer development. Because only a small proportion of infected women develop cervical cancer, other factors might be involved in carcinogenesis, either inde...

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Detalles Bibliográficos
Autores principales: Carestiato, Fernanda Nahoum, Amaro-Filho, Sergio Menezes, Moreira, Miguel Angelo Martins, Cavalcanti, Silvia Maria Baeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319029/
https://www.ncbi.nlm.nih.gov/pubmed/30569945
http://dx.doi.org/10.1590/0074-02760180456

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