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Mismatched effects of receptor interacting protein kinase-3 on hepatic steatosis and inflammation in non-alcoholic fatty liver disease

AIM: To validate the effects of receptor interacting protein kinase-3 (RIP3) deletion in non-alcoholic fatty liver disease (NAFLD) and to clarify the mechanism of action. METHODS: Wild-type (WT) and RIP3 knockout (KO) mice were fed normal chow and high fat (HF) diets for 12 wk. The body weight was a...

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Detalles Bibliográficos
Autores principales: Saeed, Waqar Khalid, Jun, Dae Won, Jang, Kiseok, Ahn, Sang Bong, Oh, Ju Hee, Chae, Yeon Ji, Lee, Jai Sun, Kang, Hyeon Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319133/
https://www.ncbi.nlm.nih.gov/pubmed/30622377
http://dx.doi.org/10.3748/wjg.v24.i48.5477