A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation

Induction of interferons during viral infection is mediated by cellular proteins that recognise viral nucleic acids. MDA5 is one such sensor of virus presence and is activated by RNA. MDA5 is required for immunity against several classes of viruses, including picornaviruses. Recent work showed that...

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Detalles Bibliográficos
Autores principales: Dias Junior, Antonio Gregorio, Sampaio, Natalia G., Rehwinkel, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319154/
https://www.ncbi.nlm.nih.gov/pubmed/30201512
http://dx.doi.org/10.1016/j.tim.2018.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319154/
https://www.ncbi.nlm.nih.gov/pubmed/30201512
http://dx.doi.org/10.1016/j.tim.2018.08.007

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