Preproinsulin Designer Antigens Excluded from Endoplasmic Reticulum Suppressed Diabetes Development in NOD Mice by DNA Vaccination

DNA vaccines against autoimmune type 1 diabetes (T1D) contain a nonpredictable risk to induce autoreactive T cell responses rather than a protective immunity. Little is known if (and how) antigen expression and processing requirements favor the induction of autoreactive or protective immune response...

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Detalles Bibliográficos
Autores principales: Stifter, Katja, Schuster, Cornelia, Krieger, Jana, Spyrantis, Andreas, Boehm, Bernhard Otto, Schirmbeck, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319196/
https://www.ncbi.nlm.nih.gov/pubmed/30623001
http://dx.doi.org/10.1016/j.omtm.2018.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319196/
https://www.ncbi.nlm.nih.gov/pubmed/30623001
http://dx.doi.org/10.1016/j.omtm.2018.12.002

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