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Efficient protection of mice from influenza A/H1N1pdm09 virus challenge infection via high avidity serum antibodies induced by booster immunizations with inactivated whole virus vaccine

The immunogenicities of inactivated whole and split virus vaccines derived from influenza A/H1N1pdm09 virus were compared in a mouse model. We demonstrated the unique properties of whole virus vaccine boosters on the serum memory antibody response in mice. Consistent with previous studies, booster i...

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Detalles Bibliográficos
Autores principales: Sato, Kayoko, Takahashi, Yoshimasa, Adachi, Yu, Asanuma, Hideki, Ato, Manabu, Tashiro, Masato, Itamura, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319303/
https://www.ncbi.nlm.nih.gov/pubmed/30623129
http://dx.doi.org/10.1016/j.heliyon.2018.e01113