Transgenerational CRISPR-Cas9 Activity Facilitates Multiplex Gene Editing in Allopolyploid Wheat

The CRISPR-Cas9-based multiplexed gene editing (MGE) provides a powerful method to modify multiple genomic regions simultaneously controlling different agronomic traits in crops. We applied the MGE construct built by combining the tandemly arrayed tRNA–gRNA units to generate heritable mutations in t...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Pan, Qianli, He, Fei, Akhunova, Alina, Chao, Shiaoman, Trick, Harold, Akhunov, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319321/
https://www.ncbi.nlm.nih.gov/pubmed/30627700
http://dx.doi.org/10.1089/crispr.2017.0010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319321/
https://www.ncbi.nlm.nih.gov/pubmed/30627700
http://dx.doi.org/10.1089/crispr.2017.0010

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