Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway

AIM: To investigate the effects of catalpol on muscular atrophy induced by sciatic nerve crush injury (SNCI). METHODS: Seventy male Kunming mice were randomized into five groups (n=10): model, sham, catalpol (Cat), rapamycin (Rapa), and catalpol+rapamycin (Rapa+Cat). The ratio of gastrocnemius muscl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yuan, Shao, Yali, Gao, Yuqing, Wan, Guoran, Wan, Dong, Zhu, Huifeng, Qiu, Yan, Ye, Xiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319426/
https://www.ncbi.nlm.nih.gov/pubmed/30643390
http://dx.doi.org/10.2147/DDDT.S188968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319426/
https://www.ncbi.nlm.nih.gov/pubmed/30643390
http://dx.doi.org/10.2147/DDDT.S188968

Ejemplares similares